The NIF is an
Open Access Microscopy and Tissue Core

servicing the Boston area (and beyond) for light microscopy and tissue processing

The Neurobiology Imaging Facility is a completely open access light microscopy and tissue core located within the Neurobiology Department.
Our mission is to advance research by providing services in optical imaging, tissue clearing, in situ hybridization as well as introduce new equipment and cutting technology to the basic science community. We provide expertise, equipment and services that are costly, time consuming and technically difficult. Our core ensures consistency and precision. We are also a teaching facility that strives to provide learning opportunities to researchers in the greater Boston area.



Phase 2 re-opening. All equipment  is available for autonomous use except the TissueCyte.

Please read our Safety Plan before you use any equipment or request services.


Available Equipment for Autonomous use :

LaVision Lightsheet GB250

VS120 #1 now in GB501C

VS120 #2 now in GB501E

FV1000 confocal in GB256

BX63 Widefield and Brightfield in GB256

Leica SPE confocal in GB501D

SP8X Confocal/STED/FLIM in GB501C

Zeiss COMBI Laser Capture/Microtweezers GB248

Workstations are available through VPN. Please contact us for access.


The TissueCyte (2photon volumetric imaging system) is available as a service.

Clearing, EM sectioning and In Situ and Slide Scanning services are also available. 


You can read our Disinfection Protocol here

You can find information regarding HMS Coronavirus Communications here




Image: Developing motor neurons and muscles in E11.5 mouse

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Can anything be more challenging than the Pan-Mass Challenge during a pandemic? Yes! Cancer. This year a NIF friend is up for the challenge. Her goal is to raise $5500 for cancer research.

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The NIF (in partnership with Thorlabs) is hosting an exciting seminar talk on 7/23 at 1pm about massive datasets & machine learning.

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