The NIF is an
Open Access Microscopy and Tissue Core

servicing the Boston area (and beyond) for light microscopy and tissue processing

The Neurobiology Imaging Facility is a completely open access light microscopy and tissue core located within the Neurobiology Department.
Our mission is to advance research by providing services in optical imaging, tissue clearing, in situ hybridization as well as introduce new equipment and cutting technology to the basic science community. We provide expertise, equipment and services that are costly, time consuming and technically difficult. Our core ensures consistency and precision. We are also a teaching facility that strives to provide learning opportunities to researchers in the greater Boston area.

 

*****ATTENTION*****

Phase 2 re-opening. All equipment  is available for autonomous use except the TissueCyte.

Please read our Safety Plan before you use any equipment or request services.

 

Available Equipment for Autonomous use :

LaVision Lightsheet GB250

VS120 #1 now in GB501C

VS120 #2 now in GB501E

FV1000 confocal in GB256

BX63 Widefield and Brightfield in GB256

Leica SPE confocal in GB501D

SP8X Confocal/STED/FLIM in GB501C

Zeiss COMBI Laser Capture/Microtweezers GB248

Workstations are available through VPN. Please contact us for access.

 

The TissueCyte (2photon volumetric imaging system) is available as a service.

Clearing, EM sectioning and In Situ and Slide Scanning services are also available. 

 

You can read our Disinfection Protocol here

You can find information regarding HMS Coronavirus Communications here

 

 

Featured Content

Dataset handling and analysis

Webinar: Large-Scale Multiphoton Imaging for Machine Learning

The NIF (in partnership with Thorlabs) is hosting a really exciting seminar talk about massive datasets and machine learning.

This has particular interest to us as we recently installed a volumetric 2-photon microscope.

I encourage anyone thinking of collecting large datasets, from slide scanning to lightsheet, to attend this webinar.

Thu, July 23, 2020

1:00 PM – 2:00 PM EDT

https://www.eventbrite.com/e/large-scale-multiphoton-imaging-for-machine-learning-tickets-110224771258
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The NIF is still closed until further notice

The NIF is still closed until further notice

Stay tuned for updates. Follow this link for more details and updates: https://www.harvard.edu/coronavirus
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Demos and Seminars Cancelled Until Further Notice

All Demos and Seminars have been cancelled

Demos and Seminars Cancelled Until Further Notice.
If you have scheduled a demo please check back with us after the corona virus apocalypse for the rescheduled itinerary.
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News

Developing motor neurons and muscles in E11.5 mouse (Jess Bell & Mary Whitman, Engle lab, BCH)

Image: Developing motor neurons and muscles in E11.5 mouse

 ... read more
PMC Beat Cancer

Can anything be more challenging than the Pan-Mass Challenge during a pandemic? Yes! Cancer. This year a NIF friend is up for the challenge. Her goal is to raise $5500 for cancer research.

 ... read more
live webinar

The NIF (in partnership with Thorlabs) is hosting an exciting seminar talk on 7/23 at 1pm about massive datasets & machine learning.

 ... read more
All News

Neurobiology Imaging Facility

220 Longwood Ave.
Goldenson 242
Boston, MA 02115

For Cores that DO have users from the EU who use Core services while on EU territory (e.g. Download and use software from HMS in their home lab; VPN from the EU to HMS compute resources to perform data analysis…), please make sure that your data use policies are consistent with the EU requirements. If you have any questions please contact Scott_edmiston@hms.harvard.edu (DBMI; Director of Research Privacy and Security Compliance) or Joseph_zurba@hms.harvard.edu (HMS information security and IT compliance officer).

Copyright © 2018 The President and Fellows of Harvard College